The mast cell: a neuroimmunoendocrine master player.
Int J Theoharides TC
Tissue React 1996;18(1):1-21
PDF Version for Download‘, ‘This review of the literature on mast cells (MC) suggests thatwhen activated they may play a central role in diseasesyndromes with a neural, immune and endocrine componentexacerbated under stress. After a discussion of their biology,differential secretions and interaction with neurons, the effect ofstress in causing MC degranulation is emphasized. Theimportance of MC in syndromes such as migraine, multiplesclerosis, interstitial cystitis and irritable bowel syndrome isassessed, along with possible therapeutic possibilities withcompounds that inhibit MC activation.
PDF Version for Download‘, ‘Publication Types:ReviewReview, academic
PMID: 8880375
PDF Version for Download